|
Albumin is a protein synthesized by the liver. It is the most abundant protein in human plasma.1 Normally it constitutes about 55 percent of all plasma proteins. Albumin performs multiple functions, including transport of many small molecules in the blood such as bilirubin, calcium, and magnesium. Albumin also binds toxins and heavy metals, thereby preventing damage they might otherwise cause. One of albumin's major roles is maintaining colloid osmotic or oncotic pressure and is therefore very important in regulating the exchange of water between plasma and the interstitial compartment.1
Talecris' albumin products, which are derived from human plasma, have an exceptional safety record. In over 60 years of production, there hasn't been a single confirmed case of virus transmission caused by our albumin products, resulting in the longest safety record of any plasma-derived product.
Certain patients, eg, those with a history of congestive cardiac failure, renal insufficiency, or stabilized chronic anemia, are at special risk of developing circulatory overload. Albumin is contraindicated in patients with a history of allergic reaction to albumin human products that are made from human plasma. Products made from human plasma may contain infectious agents, such as viruses that can cause disease.
Current prescribing information for Canadian residents is available for the following products (click on the product name to view the product monograph):
| 
